Pharmacueticals

1000202_555619541164378_173738130_n Top 25 Pharm Best Sellers:

FDA-addiction

Anti-biotic misuse

Six of the best-selling drugs have indications for forms of cancer. [©Saharrr/Fotolia.com] via Geneng (Genome Study) News: Bad press didn’t hurt Sovaldi™ (sofosbuvir)  after all. The Hepatitis C virus (HCV) treatment drew the wrath of three members of Congress, who demanded that developer Gilead Sciences justify its $84,000 price for a full 12-week treatment course of Sovaldi. The company offered its justification and didn’t have to worry about too much fallout from the criticism, since its three Congressional critics were top Democrats in the Republican-majority House of Representatives.

Even better for Gilead, which barely began marketing Sovaldi at the end of 2013, sales of the HCV treatment zoomed into eight figures—high enough to place near the top of GEN’s latest version of its List of Top 25 Best-Selling Drugs, reflecting drug sales reported for 2014.

Unlike last year’s Top 25 Best-Selling Drugs of 2013, this year’s list had only 24 drugs generating total sales of $3 billion or more. That allowed the 25th best-selling drug of 2014 to make this year’s list (it appeared in GEN’s Top 20 Best-Selling Drugs list in 2012 but missed 2013), despite sales in only the high-$2 billion range.

Biopharma is in a transition period as the blockbusters of the past decade fade. They have either fallen off the proverbial patent cliff (Novartis’ Diovan, which lost US exclusivity in 2012) or succumbed to a stronger U.S. dollar against European and Asian currencies despite rising sales (Novo Nordisk’s NovoLog, which also missed this year’s list). At the same time, the next generation of multi-billion-dollar drugs takes time to build the billions in sales needed to make the best-seller list—but can be expected to do so starting next year.

  1. What about the phrase rape of the land or rape of the countryside why is it ok for that to be used as it often is to describe violation and devastation of land but it’s not ok to describe the devastation of a Person by prescribed drugs as pharmaceutical rape.
    Rape is a very strong word and shouldn’t be used lightly but if these people had seen the devastation left behind when pharma goes wrong they might understand why the word rape has been used.
    To rape is to violate and abuse against someone’s will and that is what is happening.
    The word isn’t being used as a metaphor it is being used for what it means, rape can take place in many different scenarios it doesn’t mean exclusively sexual rape.

  2. David_Healy says:

    From Anonymous thro David Healy

    Anne Marie’s comments above were like my experience. I wasn’t only stripped naked I was assaulted several times too. I had my face rammed into the floor being suffocated, My head was then rammed into a sharp object. I had handcuffs tightened so tight I felt like shards of sharp glass were cutting into my wrists and when I screamed I was in pain they tightened then even more. I was then eventually given a gown only for that to be ripped off me again, then when I attacked them back they pulled me to the floor and rammed my head with such force into the concrete ground I thought my skull would break.

    What was my crime – like others SSRI induced alcoholism and all the problems of job loss and loss of friends and family that can go with that.

    When I came out of the cell I wanted to get a machine gun go back and take everyone of them out, I also felt like ramming my car into the central barrier of the motorway the following day. I have never felt so violated, hurt and angry in all my life.

    I imagine this is how a rape victim must feel also? I am therefore very concerned not to minimize what happens to them – the last thing I would want is to make a victim feel their suffering was less than something else. But while those of us who have not been raped can imagine how awful it is, it seems those who have not been violated by drugs don’t seem able to imagine what we have been through.

  3. John Stone says:

    I remember 40 years ago attending an Amnesty International meeting addressed by Tom Stoppard about the torture of Russian dissidents with psychiatic drugs. He didn’t completely dissociate himself from the problem of mistreatments in western psychiatric hospitals but he claimed it was a different issue. I am sure it was well meant but perhaps all you really conclude at certain level was that some people were more important than others – of course I am glad that there was support for the Russian dissidents but it doesn’t really seem that the right liberal lessons were learnt there for very long either.

    • I think the two outrages do have features in common. Simply because the people coerced in the mental health system here are usually not political dissidents, that doesn’t mean it’s not a political question. Just like the plight of millions of (mostly minority, almost all poor) Americans in prison is a political question, even though most of them are not political dissidents either.

      In both cases the victims are considered disposable people, and at least potential sources of trouble if they’re not locked up or constantly threatened with lockup. And in both cases the people actually doing the coercion are making a WHOLE lot of money out of the process. In both cases there’s a lot of reasonable voices saying this is not only cruel but irrational. Yet it’s hard as hell to make any headway against those who have an interest in continuing the outrages.

  4. Powerful stuff!

  5. Another brilliant and stunningly accurate article from Dr Healy.

    I can remember while in acute withdrawal writing a complaint to our Health commissioner and saying exactly that …’i feel like i am being mentally and psychologically raped daily while suffering and having no option but to endure wave upon wave of drug induced suicidal ideations’ this went on for two years. Finally it receded but like all monstors of horror once being raped i was then left with the complete loss of all sexual functioning, ‘Helen Keller-ed’ in the genitals, now an asexual being …i guess a punishment to ensure i never forget the perpetrator and a silent torture for the rest of my life.

    Thankyou for speaking the truth.

  6. I feel this way also after having an adverse reaction to one dose (10mg.) of citalopram. My NP told me that I should have been a better informed consumer (not patient) before I took that pill. Didn’t offer me any help or refer me to another doctor that might have been able to help me figure out what was going on in my CNS. I think she just wanted me gone at that point because the drug didn’t work like she was told it would by the drug reps. I’m in 5yrs at the end of 2015 and my nervous system is still screwed up and have some type of brain damage. So yes, it feels like I was violated without my full consent.

  7. These comments are heartening. I tried to share some of your stories with the facebook mental health support group that was offended by the use of the word “rape.” I had hoped when they heard these tragic stories they might reconsider if this usage actually trivializes experiences of sexual assault. I had hoped they might be touched as I was by the words of those of you who shared about your life-altering experiences and followed by saying you would not use the word “rape” out of respect for survivors of “real” rape. What the post generated was more outrage, so much that a few who initially agreed ended up apologizing to the bullies. Last I checked the administrator had taken the post down. I guess I need more information/input from rape survivors before I can be comfortable with this usage.

    • Sandra Villarreal says:

      I am a rape survivor. I was violently raped at knife-point, told if I didn’t do what this man wanted he was going to kill me – at 13 yrs old. Profound shame & severe PTSD followed for countless years. At 19 yrs old I was kidnapped and raped by two men I didn’t know. Profound Uncontrollable Rage and PTSD followed for countless years. The trauma from both those rapes combined comes nowhere near the trauma I suffered after going through a ‘cold turkey’ Klonopin withdrawal. When my Mental Healthcare Professions whom I was heavily involved with at the time for over a year informed me it would be ‘just fine’ to abruptly stop Klonopin, I did. When NOT one of my Mental Healthcare workers (I was under the weekly care of 7 workers, one therapist, one Psychiatrist) neglected to inform me of ANY (not one single symptom) that I may encounter from this ‘cold turkey’ withdrawal – I call this RAPE. When not one of the Mental Healthcare Professions neglected to provide any emotional or mental support while enduring up to 50 severe symptoms including Psychosis and Seizures that landed me in the Psyche ward and a trip to the Emergency Room (most of this at home alone)- I call this RAPE. I was DENIED access to my Psychiatrist at this time also. When not ONE of my Mental Healthcare workers informed me of the devastating long term Brain Impairment caused from this ‘cold turkey’ withdrawal – I call this RAPE. That withdrawal was the MOST traumatic experience I have ever endured in my 58 years on this Planet. If I would have had a gun in my house at that time, I would not be writing this today. I would have used it. I prayed for one every day to escape the Horror I was caught up in. It was complete and utter MENTAL TORTURE causing the most severe case of Post Traumatic Stress I have ever had. This is RAPE of the Mind in the most severe sense of the word. And why? Why was I refused help when I needed it most? My life depended on it. Because my Mental Healthcare Professionals are incompetent, under educated, and obviously lack compassion. And my insurance was billed $39,000. for services rendered while under their care for that year. That is 4 times what what I make in a year while on Disability caused from decades on Psychiatric Drugs. Been RAPED in body and RAPED in mind. When will this abuse ever stop?

  8. I don’t see how anyone can be offended by the word ‘rape’ – it can be used in many contexts – not just sexual ones. The fact people become alerted by it shows you have used the right word to try to convey exactly how it must feel to some people – a direct violation of their dignity without their consent.:)

  9. Who is to judge people’s experiences of traumatic events in their life. It’s not a competition of whose is the most terrible. I would never trivialize sexual rape or the victims of it for very personal reasons.
    On the other hand who is anyone else to trivialize and judge whether a Mother losing her son to suicide, a family torn apart because their loved one has killed someone, a child throwing themselves off a bridge because they’ve been pumped full of antidepressants is not as traumatic as sexual rape, how could anyone else judge if the victims of prescription drugs gone wrong are too trivial to be called pharmaceutical rape.
    We are not talking about someone who has nausea because of a new medication. We are talking about people who have been driven out of their minds, people taking their lives and the lives of others. Committing acts that would previously have been unthinkable to them. Suffering terrible mental and physical side effects. Children killing themselves and babies being born deformed because pharmaceutical companies hid data. How is that not destruction, abuse and violation towards victims who had no control over it happening.
    The trouble is they cannot and probably will not get their heads around the fact that rape is a word used to describe violation, destruction, abuse it is not a word specific to sexual rape.
    By saying that we are wrong for using the word rape in this context is hypocrisy because they are doing the very thing they complain about which is trivializing other people’s abuse.
    People who are victims of abuse whether it be sexual, physical, mental or pharmaceutical should be supporting other victims not having petty arguments over the use of a word.

  10. I am not surprised that there is an eliteist projection over semantics . No different , really , than the language manipulation that has prevented the much needed defining of the collusion between doctors and Pharma that is criminal in every sense of the word. I have met and worked with victims of medical assault and battery and victims of rape . There is more similarity than difference.

    What I believe is crucial to changing minds is the development of resonance amongst doctors and licensed prescribers , those who suffer for harm they unwittingly caused due to pharmaceutical rape. Rape is a crime. So is fraudulent business practices that cause harm . When licensed medical professionals collude with profit driven business and violate the trust of the public — I find the silence of the latter to be the most ominous sign – . Unless these crimes are named , we continue to be called consumers , clients -/ everything but the rape victims we are.

  11. I read Crazy and it was yesterday.

    What bothers me today is this……….

    However contentious Laurie’s topic – Are Seroxat/Paxil or Aropax happy with this relationship?

    ……….saving face…

    http://www.urbandictionary.com/define.php?term=language-rape

    When your ‘talking friends’ change their language from ‘Clinical Trial Transparency’ to ‘Research Transparency’, then, the 1st thing you should ask yourself, is – “can I trust my friends”?

    http://www.gsk.com/en-gb/about-us/key-achievements/

    We are the 1st pharmaceutical company to sign up to the AllTrials campaign for research transparency.

    http://www.alltrials.net/find-out-more/faq/

    GSK has said publicly that “the more eyes on our data the better for us.”

    I think we need to watch this relationship as to how we got to now and who get’s to keep their reputation…

    If there is one body I would buy a stiletto shoe for and hover it above the face of key personnel it is for Alltrials which was a moral crusade… but appeaars to have sold its soul.

    I am sure rape victims would also like to grind their heel into their attacker, but, have too much self control and try the police and courts first which often ends in complete disaster…..and they have my sympathy vote.

    I would not expect one in return.

    Pharmaceuticals are mostly insidious; it’s the gang-bang that is such an affront.

    • Annie, thank you for reading the book. Are you using the language-rape example to illustrate what many rape survivors find so offensive by my use of the definition? (It’s a really great example). And are you saying that the pharma companies who are our violators might actually benefit if we use that definition?

  12. Many good comments, and a continuing good post by Healy.

    I agree with Lisa who describes it very sensible and well.
    It’s not a competition, it’s a comparison. And the similarities are there, but no one is saying this or that about the other.

    Personally I don’t like to use the Word rape, because I’m male, but I too have been seriously harmed. But there is no doubt I have had things taken from me by “Medical force”. Or call it chemical force.

    My own naivity led me to Think I was given a “happy pill” and that was the end of it. I had no reason to research if I could become violent from these pills, since violence was never a part of my persona to begin with. And no one certainly told me this could be the case, even if you are the most loveable person out there.

    And this leaves me feeling “violated”, because I’m the only one who can say, with 100% certainty, that I would never have seen the inside of a prison if it weren’t for the pill.

    • Ove,
      Your comment rings true with me.
      My son has a neurological condition which causes him to collapse and temporary paralysis. He was prescribed an SSRI off label to try and control this. He too had no reason to research if it could cause violence because it had never been part of his persona and he had no reason to believe it would. He had never been in any kind of trouble before the SSRI.
      He took the drug believing it would help him to live a more normal life and all it has done is ruin his life. It turned him into a completely different person and has affected all of our families lives and caused a lot of distress to him, his family and others.
      So I don’t think he had any choices in the matter because he didn’t know there was any choice to make because according to the pharmaceutical company there’s no link between their drug and violent behaviour. So when the very company who make the drug don’t warn patients how is he, you or anyone else supposed to have informed choice.
      He too feels violated, he told me he no longer feels that he can trust himself in his thoughts or actions because of the total loss of control he experienced.
      The only thing I’m grateful for is that he is still alive because I truly believe that if he hadn’t been apprehended he would have killed himself.

  13. Would the word “assault” be less “offensive” to those people, and still be an accurate description?
    Given that there are people who cling to their drugs, who buy the idea that they are helpful, and who believe the hoax that is psychiatry, there has to be a better word.
    Also drugging usually isn’t one incident, it is ongoing.
    We have to get the words correct or people can’t relate.

  14. John Stone says:

    How about GBH? ‘Grievous Bodily Harm – a term in British law.

  15. I haven’t read this in its entirety, but it seems to be one of the better articles explaining where this opposition is coming from.

    https://haifischgeweint.wordpress.com/2013/03/17/rape-as-a-metaphor-for-not-rape-rape-culture-120/

  16. rape1
    /reɪp/
    noun
    1.
    the offence of forcing a person, esp a woman, to submit to sexual intercourse against that person’s will See also statutory rape
    2.
    the act of despoiling a country in warfare; rapine
    3.
    any violation or abuse: the rape of justice

    Rape is not being used as a euphemism it’s being used for the meaning of the word.
    Yes the word rape has become synonymous with sexual rape but it can and does apply to other situations as well.
    The word does not just belong to the victims of sexual rape it belongs to all victims who have been violated, abused, destroyed without their consent or knowledge.

  17. I agree with you wholeheartedly Lisa. One thing that should never be taken from victims of abuse are the words they need to describe what happened. I am going to begin writing more on this today.

    • Good for you Laurie because I think it is bullying to tell other people how they are allowed to describe any abuse or violation that happened to them and the irony is that bullying is a form of abuse.
      Words are just that, they are just tools people use to describe their feelings and thoughts. Not one person on here has disrespected sexual rape victims all we are doing is using a word in the right context to describe the atrocious abuse the pharmaceutical industry gets away with every day.

  18. It is particularly galling when you read comments written about you as ‘articulate’ and ‘above average intelligence’ several times and still you they cannot see the person, cannot think out of their box and it hits you smack in the face that something as simple as ‘talking to someone’ can lead to serious problems.

    From the front cover of Laurie’s book to the content, Laurie has defined articulate to a new level with her straightforward descriptions of how simple people can give you the ‘run around’ whilst they live in a medical strait-jacket.

    Watching other people’s behaviour can seem quite simple, eventually….and, I think this is what I learnt mostly from reading Crazy and it was by Laurie.

    I don’t think we should sell ourselves short and I don’t think we should allow other people who have sold themselves out – to profoundly hurt us with a sense of profound superiority…..it is just not on.

    http://davidhealy.org/burn-in-hell/

    February 2, 2012 at 1.03 am…….

    If I had one wish today, it would be that everyone started went back and read all the post here and on RxISK.. and got up to speed.. and then, we are all in the same frame

  19. That’s what upsets me the most about this the air of superiority that one form of abuse affects victims more than another.
    It’s shocking really that it doesn’t seem to offend them that Pharmaceutical Companies hide data, wreck people’s lives and get away with murder every day but is does offend that the word rape was used.

  20. FYI, recent paper published in JAMA Intern Med: “Research Misconduct Identified by the US Food and Drug Administration – Out of Sight, Out of Mind, Out of the Peer-Reviewed Literature”: http://archinte.jamanetwork.com/article.aspx?articleid=2109855

    Importance: Every year, the US Food and Drug Administration (FDA) inspects several hundred clinical sites performing biomedical research on human participants and occasionally finds evidence of substantial departures from good clinical practice and research misconduct. However, the FDA has no systematic method of communicating these findings to the scientific community, leaving open the possibility that research misconduct detected by a government agency goes unremarked in the peer-reviewed literature.

    Conclusions and Relevance: When the FDA finds significant departures from good clinical practice, those findings are seldom reflected in the peer-reviewed literature, even when there is evidence of data fabrication or other forms of research misconduct.

  21. John Stone says:

    If any US citizens wish to protest against forced vaccination they have ten days in which to sign this White House petition. It needs 100,000 signatures in order to get a reply: it presently has 51,858:

    https://petitions.whitehouse.gov/petition/prohibit-any-laws-mandating-force-and-requirement-vaccinations-any-kind/HW1B3YKz

  22. Sandra Villarreal says:

    I find this almost ironic when people are trying define RAPE from the stand point of true ‘rape’ compared to the Psychiatric Rape in which I’ve experienced both. I was violently raped twice in my life: at 13 yrs old and again at 19 yrs old. Both experiences left me with crippling PTSD. The only difference being, and it is a huge, devastating one to my life is that my Klonopin ‘cold turkey’ withdrawal after a 10 year addiction provided by my loving Psychiatrist was 100 times more traumatic leaving me to fight for survival on a daily basis – ALONE. When my Mental Healthcare Professionals withheld information and refused to inform me of ANY withdrawal symptoms I may encounter while under their care- this is Psychiatric RAPE! I told this to my Mental Health care therapist at the time and she looked at me as if I were Crazy, not believing a word I was saying to her. Where are we suppose to go for help when our own MEDS (DRUGS) are killing us after being on them for over 3 decades if our own Drug & Alcohol counselor’s, therapist’s & Psychiatrist’s at our local Mental Healthcare won’t believe us?

  23. Sandra Villarreal says:

    I have to add this also: While in a Psychiatric Hospital from suffering severe PTSD from my Klonopin withdrawal the previous year, extremely suicidal and Homicidal rages from that withdrawal I was Court Ordered to take Risperdal, Cogentin, Neurontin and Ambien the z-drug benzo although I begged them to treat me without using drugs and I was drug free upon arrival. While taking my ‘Court Ordered’ drugs so I wouldn’t go to jail, I took them all before bed and while under the influence of Ambien my house catches fire and burns to the ground leaving me totally homeless with no house insurance or money in which to rebuild. And the Doctors continually inform me that ‘THE BENEFITS OUT WEIGH THE RISKS!’ They are not the homeless right now – I am while struggling to live on Disability wages and move on in my life.

– See more at: http://davidhealy.org/pharmaceutical-rape/#sthash.Xvd2Onvb.dpuf

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